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The overall effect of Metformin use for PCOS is lowered testosterone levels, improved ovulation and fertility as well as a more regular menstrual cycle. As Metformin also increases the rate of ovulation, women taking Metformin for PCOS are likely to experience higher rates of pregnancy outcomes (pregnancy rates, fertility rates and abortions) and live births for their pregnancies compared to those on a placebo. Although the studies are not yet large enough to offer any meaningful conclusions about long-term benefits and risks of Metformin use for PCOS, this study, combined with the fact that Metformin is an approved drug, should give us pause to examine our own options before we decide whether or not to take this option. While I do agree that Metformin is not ideal, this study should not be interpreted as support for Metformin itself. It is an important study however, and if these results don't pan out in the long term, we may need to reconsider Metformin as our only choice of treatment options for PCOS. To conclude this article, I would like to remind everyone that for a number of reasons, it may be best to not take Metformin for PCOS unless your doctor is actively prescribing it. Metformin is a prescription medication, and we expect our current prescribing guidelines to be followed, because without that guidance, there will never be "safe" options, but only "risk" options. The bottom line is that Metformin use only for PCOS can be very dangerous. Please be careful when selecting your treatment alternatives, but most importantly, if your doctor is not aggressively prescribing Metformin, avoid it. While the results of this study are inconclusive, it would be prudent to begin Metformin treatment at an early phase of treatment. Even now, Metformin is commonly prescribed when a woman's doctor has suggested PCOS treatments. If your doctor is treating PCOS with Metformin, it is important that he/she has an ongoing discussion with you and discuss whether to continue at the same dosage (at a time when you are still a woman and not a child) in order to prevent you from receiving unwanted side effects, including weight gain. Related Article:

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